2,4-Dimethoxybenzyl alcohol is an aromatic alcohol and a substrate for glucose-methanol-choline (GMC) oxidoreductase. GMC oxidoreductase has characteristics of aryl alcohol oxidases.

Physicochemical Properties

Molecular Formula	C9H12O3
Molecular Weight	168.19
Exact Mass	168.078
CAS #	7314-44-5
PubChem CID	81750
Appearance	White to yellow <35°C powder,>39°C liquid
Density	1.1±0.1 g/cm3
Boiling Point	316.7±0.0 °C at 760 mmHg
Melting Point	38-40 °C(lit.)
Flash Point	126.8±23.2 °C
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.521
LogP	0.75
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Heavy Atom Count	12
Complexity	127
Defined Atom Stereocenter Count	0
SMILES	O(C([H])([H])[H])C1C([H])=C(C([H])=C([H])C=1C([H])([H])O[H])OC([H])([H])[H]
InChi Key	RNKOUSCCPHSCFE-UHFFFAOYSA-N
InChi Code	InChI=1S/C9H12O3/c1-11-8-4-3-7(6-10)9(5-8)12-2/h3-5,10H,6H2,1-2H3
Chemical Name	(2,4-dimethoxyphenyl)methanol
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Characterization of a new aryl-alcohol oxidase secreted by the phytopathogenic fungus Ustilago maydis. Appl Microbiol Biotechnol. 2016 Jan;100(2):697-706.

Solubility Data

Solubility (In Vitro)

DMSO: 100 mg/mL (594.57 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (14.86 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (14.86 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (14.86 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	5.9457 mL	29.7283 mL	59.4566 mL
	5 mM	1.1891 mL	5.9457 mL	11.8913 mL
	10 mM	0.5946 mL	2.9728 mL	5.9457 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.