2',4'-Dimethylacetophenone is an endogenously produced metabolite.

Physicochemical Properties

Molecular Formula	C₁₀H₁₂O
Molecular Weight	148.20
Exact Mass	148.088
CAS #	89-74-7
PubChem CID	6985
Appearance	Colorless to yellow liquid
Density	1.0±0.1 g/cm3
Boiling Point	246.5±0.0 °C at 760 mmHg
Flash Point	102.8±0.0 °C
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.510
LogP	2.59
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Heavy Atom Count	11
Complexity	151
Defined Atom Stereocenter Count	0
SMILES	O=C(C)C1C(C)=CC(C)=CC=1
InChi Key	HSDSKVWQTONQBJ-UHFFFAOYSA-N
InChi Code	InChI=1S/C10H12O/c1-7-4-5-10(9(3)11)8(2)6-7/h4-6H,1-3H3
Chemical Name	1-(2,4-dimethylphenyl)ethanone
Synonyms	2',4'Dimethylacetophenone; 2',4' Dimethylacetophenone
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

2',4'-Dimethylacetophenone is an aromatic ketone.

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~674.76 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (16.87 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (16.87 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (16.87 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	6.7476 mL	33.7382 mL	67.4764 mL
	5 mM	1.3495 mL	6.7476 mL	13.4953 mL
	10 mM	0.6748 mL	3.3738 mL	6.7476 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.