11-Mercaptoundecanoic acid (11-Thioundecanoic acid; MUA; MUDA) is a biochemical reagent that can be used as a biomaterial or organic compound related to life science research.

Physicochemical Properties

Molecular Formula	C11H22O2S
Molecular Weight	218.36
Exact Mass	218.134
CAS #	71310-21-9
PubChem CID	543502
Appearance	Solid powder
Density	0.998g/cm3
Boiling Point	352.209ºC at 760 mmHg
Melting Point	46-50ºC(lit.)
Flash Point	110ºC
Index of Refraction	1.483
LogP	3.511
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	10
Heavy Atom Count	14
Complexity	137
Defined Atom Stereocenter Count	0
SMILES	S([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H]
InChi Key	GWOLZNVIRIHJHB-UHFFFAOYSA-N
InChi Code	InChI=1S/C11H22O2S/c12-11(13)9-7-5-3-1-2-4-6-8-10-14/h14H,1-10H2,(H,12,13)
Chemical Name	11-sulfanylundecanoic acid
Synonyms	11-Thioundecanoic acid; MUA; MUDA; 11-Mercaptoundecanoic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Biochemical reagents[M]//Methods of Enzymatic Analysis. Academic Press, 1965: 967-1037.

Solubility Data

Solubility (In Vitro)

DMSO : 200 mg/mL (915.92 mM; with sonication)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (11.45 mM)(Saturation unknown) in 10% DMSO 40% PEG300 5% Tween-80 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution, add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix well; then add 50 μL Tween-80 to the above system and mix well; then add 450 μL saline to make up to 1 mL. *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (11.45 mM)(Saturation unknown) in 10% DMSO 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution, add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD in saline and mix well. *Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.5796 mL	22.8980 mL	45.7959 mL
	5 mM	0.9159 mL	4.5796 mL	9.1592 mL
	10 mM	0.4580 mL	2.2898 mL	4.5796 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.