1-Tetradecanol, extracted from Myristica fragrans, is a linear saturated fatty alcohol with antibacterial and anti~inflammatory activity.

Physicochemical Properties

Molecular Formula	C14H30O
Molecular Weight	214.39
Exact Mass	214.229
CAS #	112-72-1
Related CAS #	1-Tetradecanol-d29;284474-78-8;1-Tetradecanol-d2;169398-02-1
PubChem CID	8209
Appearance	White to off-white solid powder
Density	0.8±0.1 g/cm3
Boiling Point	263.2±0.0 °C at 760 mmHg
Melting Point	35-39 °C(lit.)
Flash Point	125.9±4.6 °C
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.445
LogP	6.19
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	12
Heavy Atom Count	15
Complexity	102
Defined Atom Stereocenter Count	0
InChi Key	HLZKNKRTKFSKGZ-UHFFFAOYSA-N
InChi Code	InChI=1S/C14H30O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h15H,2-14H2,1H3
Chemical Name	tetradecan-1-ol
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Design and fabrication of reversible thermochromic microencapsulated phase change materials for thermal energy storage and its antibacterial activity. Energy. Volume 159, 15 September 2018, Pages 857-869.

Additional Infomation

Tetradecanol is a colorless thick liquid (heated) with a faint alcohol odor. Solidifies and floats on water. (USCG, 1999) Tetradecan-1-ol is a long-chain fatty alcohol that is tetradecane substituted by a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and a pheromone. It is a long-chain primary fatty alcohol and a tetradecanol. 1-Tetradecanol has been reported in Angelica gigas, Fusarium fujikuroi, and other organisms with data available. See also: Alcohols, C10-16 (annotation moved to); Alcohols, C12-16 (annotation moved to); Alcohols, C14-15 (annotation moved to) ... View More ...

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~466.44 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (11.66 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (11.66 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.6644 mL	23.3220 mL	46.6440 mL
	5 mM	0.9329 mL	4.6644 mL	9.3288 mL
	10 mM	0.4664 mL	2.3322 mL	4.6644 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.