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1-Methylguanidine hydrochloride 21770-81-0

1-Methylguanidine hydrochloride 21770-81-0

CAS No.: 21770-81-0

1-Methylguanidine HCl is an endogenously produced metabolite.
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This product is for research use only, not for human use. We do not sell to patients.

1-Methylguanidine HCl is an endogenously produced metabolite.

Physicochemical Properties


Molecular Formula C2H8CLN3
Molecular Weight 109.56
Exact Mass 109.041
CAS # 21770-81-0
PubChem CID 146724
Appearance White to off-white solid powder
Density 1.22 g/mL at 20 °C(lit.)
Boiling Point 72 °C
Melting Point -20 °C
Flash Point 65 °F
Index of Refraction n20/D 1.4279(lit.)
LogP 1.092
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 1
Rotatable Bond Count 0
Heavy Atom Count 6
Complexity 42.9
Defined Atom Stereocenter Count 0
InChi Key VJQCNCOGZPSOQZ-UHFFFAOYSA-N
InChi Code

InChI=1S/C2H7N3.ClH/c1-5-2(3)4;/h1H3,(H4,3,4,5);1H
Chemical Name

2-methylguanidine;hydrochloride
HS Tariff Code 2934.99.9001
Storage

Powder-20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity


Additional Infomation 1-Methylguanidine hydrochloride is a member of guanidines.

Solubility Data


Solubility (In Vitro) H2O: 250 mg/mL (2281.85 mM)
Solubility (In Vivo) Solubility in Formulation 1: 100 mg/mL (912.74 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.

 (Please use freshly prepared in vivo formulations for optimal results.)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 9.1274 mL 45.6371 mL 91.2742 mL
5 mM 1.8255 mL 9.1274 mL 18.2548 mL
10 mM 0.9127 mL 4.5637 mL 9.1274 mL
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.