(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside is extracted from the bark part of Albizia julibrissin.

Physicochemical Properties

Molecular Formula	C33H44O17
Molecular Weight	712.6923
Exact Mass	712.257
CAS #	136997-64-3
Appearance	White to yellow solid powder
Density	1.5±0.1 g/cm3
Boiling Point	935.3±65.0 °C at 760 mmHg
Flash Point	519.5±34.3 °C
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.653
LogP	-0.25
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Lignan glycosides from bark of Albizzia myriophylla. Phytochemistry. 1994 Nov;37(5):1455-8.

Additional Infomation

(-)-Syringaresinol 4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside is a lignan glycoside isolated from the bark of the plant Albizzia myriophylla. It was identified as Compound 1 in the study.[1] The molecular formula was determined to be C33H44O17 based on high-resolution FAB-mass spectrometry (negative ion mode, [M-H]- peak at m/z 711.2496).[1] Its structure was confirmed by comparison of its 13C NMR spectral data with those of a previously identified compound from another Albizzia species.[1] Enzymatic hydrolysis of this compound using crude hesperidinase yielded the aglycone, which was identified as (-)-syringaresinol based on optical rotation and 13C NMR data.[1] The study was part of a search for sweet-tasting principles from A. myriophylla, but this compound was not sweet.[1]

Solubility Data

Solubility (In Vitro)

DMSO : ~100 mg/mL (~140.31 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.08 mg/mL (2.92 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.08 mg/mL (2.92 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.08 mg/mL (2.92 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 20.8 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.4031 mL	7.0157 mL	14.0313 mL
	5 mM	0.2806 mL	1.4031 mL	2.8063 mL
	10 mM	0.1403 mL	0.7016 mL	1.4031 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.