(R)-BINAP is a biochemical compound that may be utilized as a biomaterial or organic/chemical reagent for biomedical research.

Physicochemical Properties

Molecular Formula	C44H32P2
Molecular Weight	622.67
Exact Mass	622.197
CAS #	76189-55-4
Related CAS #	(Rac)-BINAP;98327-87-8;(S)-BINAP;76189-56-5
PubChem CID	634876
Appearance	White to off-white solid powder
Boiling Point	724.3±55.0 °C at 760 mmHg
Melting Point	283-286 °C(lit.)
Flash Point	419.0±37.8 °C
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	235 ° (C=0.3, Toluene)
LogP	13.38
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	7
Heavy Atom Count	46
Complexity	797
Defined Atom Stereocenter Count	0
SMILES	[C@@]1([C@]2=C3C=CC=CC3=CC=C2P(C4=CC=CC=C4)C5=CC=CC=C5)=C6C=CC=CC6=CC=C1P(C7=CC=CC=C7)C8=CC=CC=C8
InChi Key	MUALRAIOVNYAIW-UHFFFAOYSA-N
InChi Code	InChI=1S/C44H32P2/c1-5-19-35(20-6-1)45(36-21-7-2-8-22-36)41-31-29-33-17-13-15-27-39(33)43(41)44-40-28-16-14-18-34(40)30-32-42(44)46(37-23-9-3-10-24-37)38-25-11-4-12-26-38/h1-32H
Chemical Name	[1-(2-diphenylphosphanylnaphthalen-1-yl)naphthalen-2-yl]-diphenylphosphane
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro

In metal-mediated asymmetric catalysis, (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthy is employed as a chiral ligand.

Solubility Data

Solubility (In Vitro)

DMSO: 5 mg/mL (8.03 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 0.5 mg/mL (0.80 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 5.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.6060 mL	8.0299 mL	16.0599 mL
	5 mM	0.3212 mL	1.6060 mL	3.2120 mL
	10 mM	0.1606 mL	0.8030 mL	1.6060 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.