(±)-Jasmonic acid is a plant growth regulator and an analogue of α-linolenic acid. (±)-Jasmonic acid reduces chlorophyll levels in green and etiolated barley leaf segments and inhibits rice seedling elongation.

Physicochemical Properties

Molecular Formula	C12H18O3
Molecular Weight	210.27
Exact Mass	196.109
CAS #	77026-92-7
Related CAS #	(±)-Jasmonic acid-d5;2750534-78-0;Jasmonic acid;6894-38-8;Jasmonic acid-d5;1821807-88-8
PubChem CID	5281166
Appearance	Colorless to light yellow liquid
Density	1.1±0.1 g/cm3
Boiling Point	350.8±15.0 °C at 760 mmHg
Flash Point	180.2±16.9 °C
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.492
LogP	1.13
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Heavy Atom Count	15
Complexity	268
Defined Atom Stereocenter Count	2
SMILES	CC/C=C\C[C@H]1[C@@H](CCC1=O)CC(=O)O
InChi Key	ZNJFBWYDHIGLCU-HWKXXFMVSA-N
InChi Code	InChI=1S/C12H18O3/c1-2-3-4-5-10-9(8-12(14)15)6-7-11(10)13/h3-4,9-10H,2,5-8H2,1H3,(H,14,15)/b4-3-/t9-,10-/m1/s1
Chemical Name	2-[(1R,2R)-3-oxo-2-[(Z)-pent-2-enyl]cyclopentyl]acetic acid
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

Additional Infomation

Jasmonic acid is an oxo monocarboxylic acid that is (3-oxocyclopentyl)acetic acid substituted by a (2Z)-pent-2-en-1-yl group at position 2 of the cyclopentane ring. It has a role as a plant metabolite and a member of jasmonates. It is a conjugate acid of a jasmonate(1-). It is an enantiomer of a (+)-jasmonic acid. Jasmonic acid has been reported in Gelidium latifolium, Fusarium fujikuroi, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

DMSO: 100 mg/mL (475.58 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (11.89 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (11.89 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 3: ≥ 2.5 mg/mL (11.89 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.7558 mL	23.7790 mL	47.5579 mL
	5 mM	0.9512 mL	4.7558 mL	9.5116 mL
	10 mM	0.4756 mL	2.3779 mL	4.7558 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.