| Description | (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats. |
| In vivo | 糖尿病大鼠连续28天内给予myrtenal (80 mg/kg bw)治疗。结果显示，糖尿病大鼠的血浆葡萄糖水平升高，血浆胰岛素水平降低，同时在肝脏中胰岛素受体底物2 (IRS2)、Akt 以及葡萄糖转运蛋白2 (GLUT2) 的表达下调，在骨骼肌中胰岛素受体底物2 (IRS2)、Akt 以及葡萄糖转运蛋白4 (GLUT4) 的蛋白表达也呈现下降[1]。 |
| Synonyms | (1R)-(-)-桃金娘烯醛, 桃金娘烯醛, (1R)-(−)-Myrtenal |
| molecular weight | 150.22 |
| Molecular formula | C10H14O |
| CAS | 18486-69-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30 mg/mL (199.71 mM) |
| References | 1. Rathinam A , Pari L . Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats[J]. Chemico-Biological Interactions, 2016:S0009279716302836. 2. Rathinam A , Pari L , Venkatesan M , et al. Myrtenal attenuates oxidative stress and inflammation in a rat model of streptozotocin-induced diabetes[J]. |