| Description | ZY-444 has potential anticancer activity, inhibits PCa cell proliferation and metastasis, and inhibits the growth of subcutaneous tumors. |
| molecular weight | 444.59 |
| Molecular formula | C26H28N4OS |
| CAS | 1802650-31-2 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 80 mg/mL (179.94 mM), Sonication is recommended. |
| References | 1. Lin Q, et al. Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression. Adv Sci (Weinh). 2020 Mar 12;7(9):1903483. 2. Han MT, et al. ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway. Am J Cancer Res. 2023 Apr 15;13(4):1533-1546. |