| Description | ZTZ240, a KCNQ2 K+ channel activator, offers a new target to treat hyperexcitability disorders. |
| Synonyms | ZTZ 240, ZTZ-240 |
| molecular weight | 250.66 |
| Molecular formula | C12H8ClFN2O |
| CAS | 325457-98-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Kornilov P, Peretz A, Attali B. Channel gating pore: a new therapeutic target. Cell Res. 2013 Sep;23(9):1067-8. doi: 10.1038/cr.2013.89. Epub 2013 Jul 9. PubMed PMID: 23835478; PubMed Central PMCID: PMC3760620. |
| Citations | 1. Chen F, Gao Q, Wei A, et al. Histone deacetylase 3 aberration inhibits Klotho transcription and promotes renal fibrosis. Cell Death & Differentiation. 2020: 1-12 |