| Description | Zoliprofen is a potent and orally available non-steroidal anti-inflammatory agent with anti-inflammatory, antipyretic and analgesic activity, and inhibits carobolin, mycobacterium, and knife-ball protein A-induced rat paw oedema, as well as anti-rat serum-induced fracture or dorsal skin oedema. Zoliprofen is 20 times more effective than ibuprofen and fenoprofen against collagen- or arachidonic acid-induced platelet aggregation in rats and rabbits. Zoliprofen was 20 times more effective than ibuprofen and fenoprofen in inhibiting endotoxin-induced diarrhoea in mice and arachidonic acid-induced acute mortality in rabbits. |
| molecular weight | 249.29 |
| Molecular formula | C12H11NO3S |
| CAS | 56355-17-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 22.5 mg/mL (90.26 mM) |
| References | 1. Hong Dae Choi, et al. Synthesis of 4-(2-thiazolyloxy)phenylalkanoic acids as an antiinflammatory agent. 1996 ; 19: Archives of Pharmacal Research.148–152. |