| Description | Zolimidine, an imidazopyridine derivative, functions as an orally active antiulcer agent. It promotes mucus secretion in intestinal mucosal cells and enhances the intestinal wall's resistance to ulceration. Studies demonstrate its gastroprotective effect in duodenal ulcer research [1] [2]. |
| In vivo | Zolimidine（200 mg/kg；口服）有效减少了由Indomethacin（HY-14397）（5 mg/kg/天，连续8天，直肠给药）引起的大鼠肠溃疡发生率[2]。此外，Zolimidine在饮食中以1%的浓度添加，能显著降低豚鼠因摄入含5%角叉菜胶的饮用水（持续40天）而产生的肠溃疡发生率[2]。 |
| molecular weight | 272.32 |
| Molecular formula | C14H12N2O2S |
| CAS | 1222-57-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |