| Description | Zilovertamab (UC-961) is a humanized anti-ROR1 monoclonal antibody that cuts off the WNT5A-induced ROR1 signaling pathway and shows anti-proliferative activity in ovarian and endometrial cancer cells. It can be used to study lymphatic cancer. |
| In vitro | Zilovertamab（25和50 µg/mL；72小时）能够抑制高级浆液性卵巢癌（HGSOC）细胞的增殖[1]。Zilovertamab（50 µg/mL；72小时）在转录水平上下调CaOV3中ROR1的表达水平[1]。 |
| Synonyms | Cirmtuzumab, UC-961 |
| molecular weight | N/A |
| CAS | 1643432-38-5 |
| Storage | store at low temperature | store at -80°C |
| References | 1. Liu D, et, al. The Anti-ROR1 Monoclonal Antibody Zilovertamab Inhibits the Proliferation of Ovarian and Endometrial Cancer Cells. Pharmaceutics. 2022 Apr 11;14(4):837. |