| Description | Zeniplatin (Zeniplatinum) is a new cisplatin complex with anticancer activity for the treatment of metastatic melanoma and kidney cancer. |
| Synonyms | Zeniplatinum |
| molecular weight | 471.36 |
| Molecular formula | C11H20N2O6Pt |
| CAS | 111490-36-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (116.68 mM) |
| References | 1. Aamdal S, Bruntsch U, Kerger J, Verweij J, ten Bokkel Huinink W, Wanders J, Rastogi R, Franklin HR, Kaye SB. Zeniplatin in advanced malignant melanoma and renal cancer: phase II studies with unexpected nephrotoxicity. Cancer Chemother Pharmacol. 1997;40(5):439-43. PubMed PMID: 9272122. 2. Olver I, Green M, Peters W, Zimet A, Toner G, Bishop J, Ketelbey W, Rastogi R, Birkhofer M. A phase II trial of zeniplatin in metastatic melanoma. Am J Clin Oncol. 1995 Feb;18(1):56-8. PubMed PMID: 7847260. 3. DeMarco LC, Budman DR, Lathia C, Amorusi P, Birkhofer M, Lichtman S, Weiselberg L, Vinciguerra V, Lovecchio J, Gal D, et al. Pharmacokinetic evaluation of zeniplatin in humans. Cancer Chemother Pharmacol. 1995;36(1):35-40. PubMed PMID: 7720173. 4. Sorensen JB. Treatment of non-small cell lung cancer: new cytostatic agents. Lung Cancer. 1993 Dec;10(3-4):173-87. Review. PubMed PMID: 8075965. |