| Description | Z433927330 is a potent and selective Aquaporin-7 (AQP7) inhibitor(IC50s of 0.2). |
| In vitro | Z433927330 抑制甘油透过性（IC50：0.6 μM）。 |
| Target activity | AQP9 (mouse):~1.1 µM , AQP3 (mouse):~0.7 µM , AQP7 (mouse):~0.2 µM |
| molecular weight | 364.4 |
| Molecular formula | C20H20N4O3 |
| CAS | 1005883-72-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 280 mg/mL (768.39 mM) |
| References | 1. Z433927330, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294(18):7377-7387. |