| Description | Z-Glycine (Carbobenzoxyglycine) is a drug-lipid conjugates designed to promote brain penetration based on its lipophilicity and resemblance to lipids in biological membranes[1]. |
| Synonyms | Carbobenzoxyglycine, N-苄氧羰基-甘氨酸, N-Carbobenzoxyglycine |
| molecular weight | 209.2 |
| Molecular formula | C10H11NO4 |
| CAS | 1138-80-3 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (262.91 mM) |
| References | 1. Lambert DM. Rationale and applications of lipids as prodrug carriers. Eur J Pharm Sci. 2000 Oct;11 Suppl 2:S15-27. 2. Lambert DM. Rationale and applications of lipids as prodrug carriers. Eur J Pharm Sci. 2000 Oct;11 Suppl 2:S15-27. Review. PubMed PMID: 11033424. 3. Scriba GK, Lambert DM. Synthesis and anticonvulsant activity of N-benzyloxycarbonyl-amino acid prodrugs of phenytoin. J Pharm Pharmacol. 1999 May;51(5):549-53. PubMed PMID: 10411214. 4. Sussan S, Dagan A, Bialer M. Pharmacokinetic analysis and anticonvulsant activity of glycine and glycinamide derivatives. Epilepsy Res. 1999 Jan;33(1):11-21. PubMed PMID: 10022362. |