| Description | YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression. This compound exhibits high-affinity physical interaction with ALDH18A1, which may influence its enzymatic activity [1]. |
| In vivo | YG1702(腹腔注射,45 mg/kg,隔日给药,共三次)能够有效抑制荷瘤小鼠异种移植物生长[1]。 |
| molecular weight | 478.56 |
| Molecular formula | C23H30N2O7S |
| CAS | 724737-08-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |