| Description | XC-302 is a multi-targeted inhibitor, it induces autophagy of nasopharyngeal cancer cells via inhibiting the PI3K/AKT/mTOR signaling pathway. |
| Synonyms | XC 302, Puquitinib, XC-302, XC302 |
| molecular weight | 317.35 |
| Molecular formula | C17H15N7 |
| CAS | 916890-10-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Wang KF, Yang H, Jiang WQ, Li S, Cai YC. Puquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cells. Int J Mol Med. 2015 Dec;36(6):1556-62. doi: 10.3892/ijmm.2015.2378. PubMed PMID: 26499488; PubMed Central PMCID: PMC4678157. 2. Yang H, Wang Y, Zhan J, Xia Y, Sun P, Bi XW, Liu PP, Li ZM, Li S, Zou BY, Jiang WQ. Puquitinib mesylate, an inhibitor of phosphatidylinositol 3-kinase p110δ, for treating relapsed or refractory non-Hodgkin's lymphoma. Oncotarget. 2015 Dec 22;6(41):44049-56. doi: 10.18632/oncotarget.5833. PubMed PMID: 26510909; PubMed Central PMCID: PMC4791286. |