| Description | WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 nM, respectively). |
| Target activity | ROS1:1.1 nM , ALK:1.4 nM |
| molecular weight | 612.15 |
| Molecular formula | C28H34ClN9O3S |
| CAS | 2163060-83-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Wang Y, et al. Discovery of novel 2,4-diarylaminopyrimidine analogues as ALK and ROS1 dual inhibitors to overcome crizotinib-resistant mutants including G1202R. Eur J Med Chem. 2018 Jan 1;143:123-136. |