| Description | WST-1 is a cytotoxic, water-soluble tetrazolium salt that induces intracellular mitochondrial dehydrogenases to undergo NADH-dependent enzymatic reactions, releasing water-soluble methylbenzene products.WST-1 can be used to detect cell proliferation and cellular activity by assaying the uptake values, and can be used to determine superoxide dismutase activity in the WST-1 plate assay. |
| Synonyms | WST 1 |
| molecular weight | 651.34 |
| Molecular formula | C19H11IN5NaO8S2 |
| CAS | 150849-52-8 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (76.65 mM), Sonication is recommended. H2O: 0.1 mg/mL (insoluble), when pH is adjusted to 9 with NaOH. Sonication and heating to 80℃ are recommended. |
| References | 1. Bahadar H, et al. Toxicity of Nanoparticles and an Overview of Current Experimental Models. Iran Biomed J. 2016;20(1):1-1 2. Błaszczak-Świątkiewicz K, et al. Some characteristics of activity of potential chemotherapeutics--benzimidazole derivatives. Adv Med Sci. 2015 Mar;60(1):125-3 3. Tournebize J, et al. Pitfalls of assays devoted to evaluation of oxidative stress induced by inorganic nanoparticles. Talanta. 2013 Nov 15;116:753-6 4. Winkler C, et al. The bacterial adhesion on and the cytotoxicity of various dental cements used for implant-supported fixed restorations. Acta Odontol Scand. 2014 May;72(4):241-50. |