| Description | WRC-0571 is a highly potent, selective antagonist of A1 adenosine receptors. |
| molecular weight | 330.43 |
| Molecular formula | C17H26N6O |
| CAS | 501667-77-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Clark AN, Youkey R, Liu X, Jia L, Blatt R, Day YJ, Sullivan GW, Linden J, Tucker AL. A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circ Res. 2007 Nov 26;101(11):1130-8. Epub 2007 Sep 27. PubMed PMID: 17901362. 2. Shryock JC, Ozeck MJ, Belardinelli L. Inverse agonists and neutral antagonists of recombinant human A1 adenosine receptors stably expressed in Chinese hamster ovary cells. Mol Pharmacol. 1998 May;53(5):886-93. PubMed PMID: 9584215. 3. Jin X, Shepherd RK, Duling BR, Linden J. Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation. J Clin Invest. 1997 Dec 1;100(11):2849-57. PubMed PMID: 9389751; PubMed Central PMCID: PMC508491. 4. Auchampach JA, Jin X, Wan TC, Caughey GH, Linden J. Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor. Mol Pharmacol. 1997 Nov;52(5):846-60. PubMed PMID: 9351976. |