PeptideDB

WR23

CAS No.: 1350960-66-5

WR23 is a piperidinylquinoxaline derivative and a phosphoinositide 3-kinase α (PI3Kα) inhibitor.
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Description WR23 is a piperidinylquinoxaline derivative and a phosphoinositide 3-kinase α (PI3Kα) inhibitor.
Synonyms WR 23, WR-23
molecular weight 448.33
Molecular formula C19H18BrN3O3S
CAS 1350960-66-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Wu P, Su Y, Liu X, Yang B, He Q, Hu Y. Discovery of novel 2-piperidinol-3-(arylsulfonyl)quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors. Bioorg Med Chem. 2012 May 1;20(9):2837-44. doi: 10.1016/j.bmc.2012.03.026. Epub 2012 Mar 17. PubMed PMID: 22480851. 2. Wu P, Su Y, Guan X, Liu X, Zhang J, Dong X, Huang W, Hu Y. Identification of novel piperazinylquinoxaline derivatives as potent phosphoinositide 3-kinase (PI3K) inhibitors. PLoS One. 2012;7(8):e43171. doi: 10.1371/journal.pone.0043171. Epub 2012 Aug 14. PubMed PMID: 22905224; PubMed Central PMCID: PMC3419191. 3. Kuopio T, Kankaanranta A, Jalava P, Kronqvist P, Kotkansalo T, Weber E, Collan Y. Cysteine proteinase inhibitor cystatin A in breast cancer. Cancer Res. 1998 Feb 1;58(3):432-6. PubMed PMID: 9458085.