| Description | WIN 51,708 is a neurokinin receptor (NK1) antagonist. |
| In vivo | 在METH前30分钟穿过血脑屏障的非肽神经激肽-1受体拮抗剂WIN-51,708（5 mg/kg，IP）的雄性小鼠全身注射显著减弱了通过HPLC测量的METH诱导的3-NT纹状体产生。[1] |
| Synonyms | WIN51,708, WIN-51,708 |
| molecular weight | 439.59 |
| Molecular formula | C29H33N3O |
| CAS | 144177-30-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Afanador L, et al. Contrasting Effects of the Neuropeptides Substance P, Somatostatin, and Neuropeptide Y on the Methamphetamine-Induced Production of Striatal Nitric Oxide in Mice. J Drug Alcohol Res. 2012;pii: 235604. |