| Description | Way 120491 activates ATP-sensitive potassium channels. |
| Synonyms | Way120491, Way-120,491, Way-120491, Celikalim |
| molecular weight | 393.36 |
| Molecular formula | C20H18F3NO4 |
| CAS | 124916-54-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. de Lorenzi FG. Celikalim (WAY-120491) increases K+ outward flux in dog and human airway smooth muscle. Pulm Pharmacol. 1994 Apr;7(2):129-35. PubMed PMID: 8081073. 2. Wojdan A, Freeden C, Woods M, Oshiro G, Spinelli W, Colatsky TJ, Sheldon JH, Norton NW, Warga D, Antane MM, Antane SA, Butera JA, Argentieri TM. Comparison of the potassium channel openers, WAY-133537, ZD6169, and celikalim on isolated bladder tissue and In vivo bladder instability in rat. J Pharmacol Exp Ther. 1999 Jun;289(3):1410-8. PubMed PMID: 10336534. 3. Furspan PB. WAY 120,491 activates ATP-sensitive potassium channels in rat tail artery. Eur J Pharmacol. 1992 Nov 17;223(2-3):201-3. PubMed PMID: 1478268. 4. Evans JM, Smith RJ, Stemp G. Separation of the enantiomers of some potassium channel activators using an alpha 1-acid glycoprotein column. J Chromatogr. 1992 Oct 9;623(1):163-7. PubMed PMID: 1452627. |