Description | W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist. |
In vitro | W-5 hydrochloride 抑制HR和KF细胞的增殖,其IC50分别为6.4μM和8.6μM[1]。 |
Synonyms | W-5 HCl, 盐酸W-5, W 5 (hydrochloride), N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl |
molecular weight | 342.88 |
Molecular formula | C16H23ClN2O2S |
CAS | 61714-25-8 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 3.43 mg/mL (10 mM), Sonication is recommended. |
References | 1. Kikuchi Y, Iwano I, Kato K. Effects of calmodulin antagonists on human ovarian cancer cell proliferation in vitro. Biochem Biophys Res Commun. 1984 Aug 30;123(1):385-92. |