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W-5 hydrochloride

CAS No.: 61714-25-8

W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist.
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Description W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist.
In vitro W-5 hydrochloride 抑制HR和KF细胞的增殖,其IC50分别为6.4μM和8.6μM[1]。
Synonyms W-5 HCl, 盐酸W-5, W 5 (hydrochloride), N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl
molecular weight 342.88
Molecular formula C16H23ClN2O2S
CAS 61714-25-8
Storage store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 3.43 mg/mL (10 mM), Sonication is recommended.
References 1. Kikuchi Y, Iwano I, Kato K. Effects of calmodulin antagonists on human ovarian cancer cell proliferation in vitro. Biochem Biophys Res Commun. 1984 Aug 30;123(1):385-92.