| Description | VUF5834 is a full inverse agonist of CXCR3 N3.35A. |
| Synonyms | VUF-5834, VUF 5834 |
| molecular weight | 515.69 |
| Molecular formula | C31H41N5O2 |
| CAS | 860002-95-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Verzijl D, Storelli S, Scholten DJ, Bosch L, Reinhart TA, Streblow DN, Tensen CP, Fitzsimons CP, Zaman GJ, Pease JE, de Esch IJ, Smit MJ, Leurs R. Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors. J Pharmacol Exp Ther. 2008 May;325(2):544-55. doi: 10.1124/jpet.107.134783. Epub 2008 Feb 12. PubMed PMID: 18270317; PubMed Central PMCID: PMC3659174. |