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VU661

CAS No.: 37648-76-3

VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening.
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Description VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening.
In vitro VU661(浓度为1、3、10μM;作用时间0-144小时)表现出剂量相关的周期延长作用(10μM时延长约7.2小时),对Bmal1-dLuc U2OS细胞系律动的振幅影响甚微[1]。此外,VU661(浓度为1、10μM;作用时间24小时)在细胞内剂量依赖性地增加光学氧化还原比[1]。同时,VU661对细胞ROS或H2O2水平基本上不产生影响[1]。
molecular weight 299.33
Molecular formula C19H13N3O
CAS 37648-76-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year