| Description | VU625 (VU007625) is a selective and potent AeKir1 inhibitor (IC50: 96.8 nM) that acts as a mosquito killer and inhibits AeKir1-mediated currents. |
| Synonyms | VU 625, VU-007625, VU-625, VU 007625, VU007625 |
| molecular weight | 374.45 |
| Molecular formula | C19H22N2O4S |
| CAS | 901008-62-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Beyenbach KW, et al. Targeting renal epithelial channels for the control of insect vectors. Tissue Barriers. 2015 Sep 1;3(4):e1081861. 2. Piermarini PM, et al. Localization and role of inward rectifier K(+) channels in Malpighian tubules of the yellow fever mosquito Aedes aegypti. Insect Biochem Mol Biol. 2015 Dec;67:59-73. 3. Raphemot R,et al. Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels. PLoS One. 2014 Nov 6;9(11):e110772. doi: 10.1371/journal.pone.0110772. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119883. |