| Description | VU6004256 is a selective positive allosteric modulator (PAM) of muscarinic receptor M1. |
| Synonyms | VU 6004256, VU-6004256 |
| molecular weight | 465.5 |
| Molecular formula | C25H25F2N5O2 |
| CAS | 2011034-33-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Grannan MD, Mielnik CA, Moran SP, Gould RW, Ball J, Lu Z, Bubser M, Ramsey AJ, Abe M, Cho HP, Nance KD, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW, Jones CK. Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M(1) PAM VU6004256. ACS Chem Neurosci. 2016 Dec 21;7(12):1706-1716. doi: 10.1021/acschemneuro.6b00230. Epub 2016 Oct 5. PubMed PMID: 27617634; PubMed Central PMCID: PMC5231396. |