| Description | VPC32183 is a competitive antagonist of LPA1 and LPA3 receptors. |
| Synonyms | VPC-32183, VPC 32183 |
| molecular weight | 602.74 |
| Molecular formula | C33H51N2O6P |
| CAS | 717110-61-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Violet PC, Billon-Denis E, Robin P. Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK(1/2) MAP kinases. Biochim Biophys Acta. 2012 Nov;1821(11):1394-405. doi: 10.1016/j.bbalip.2012.07.009. Epub 2012 Jul 20. PubMed PMID: 22820196. 2. Kim K, Kim HL, Lee YK, Han M, Sacket SJ, Jo JY, Kim YL, Im DS. Lysophosphatidylserine induces calcium signaling through Ki16425/VPC32183-sensitive GPCR in bone marrow-derived mast cells and in C6 glioma and colon cancer cells. Arch Pharm Res. 2008 Mar;31(3):310-7. doi: 10.1007/s12272-001-1157-x. Epub 2008 Apr 13. PubMed PMID: 18409043. |