Description | Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals. |
In vitro | 对Strychnos icaja Baillon的再次研究导致了Vomicine、isostrychnine以及三种新的sungucine衍生物的分离,这些衍生物分别命名为isosungucine (8)、18-hydroxy-sungucine (9)和18-hydroxy-isosungucine (10)。它们通过详细的光谱方法被鉴定。同时,对sungucine进行了完整的1H和13C-NMR研究。部分化合物在体外对抗疟原虫Plasmodium falciparum,特别是对抵抗氯喹的菌株表现出高度活性[1]。 |
Synonyms | 番木虌次碱, 番木鳖次碱 |
molecular weight | 380.44 |
Molecular formula | C22H24N2O4 |
CAS | 125-15-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | DMSO: 50 mg/mL (131.43 mM) |
References | 1. New antimalarial and cytotoxic sungucine derivatives from Strychnos icaja roots.Planta Med. 2000 Apr;66(3):262-9. |