| Description | Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase. |
| In vitro | Visnagin能够放松先前被去甲肾上腺素收缩的主动脉，并且弱地抑制环核苷酸磷酸二酯酶（PDE）同工酶（PDE5, PDE4, PDE3, 循环GMP激活的PDE2及PDE1）的水解活性。 |
| molecular weight | 230.22 |
| Molecular formula | C13H10O4 |
| CAS | 82-57-5 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 25 mg/mL (108.59 mM) |
| References | 1. Radim Vrzal, et al. Khellin and Visnagin Differentially Modulate AHR Signaling and Downstream CYP1A Activity in Human Liver Cells. PLoS One. 2013 Sep 19;8(9):e74917. 2. Min-Soo Kwon, et al. Neuroprotective Effect of Visnagin on Kainic Acid-induced Neuronal Cell Death in the Mice Hippocampus. Korean J Physiol Pharmacol. 2010 Oct;14(5):257-63. 3. J Duarte, et al. Cardiovascular Effects of Visnagin on Rats. Planta Med. 2000 Feb;66(1):35-9. |