| Description | Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 demonstrated pangenotypic antiviral activity in patients with genotype 1-4 HCV infection. It will be further evaluated in combination with other pangenotypic direct-acting antivirals to achieve the goal of developing a well-tolerated, highly effective treatment for all HCV genotypes. |
| Synonyms | GS-5816, 维帕他韦 |
| molecular weight | 883 |
| Molecular formula | C49H54N8O8 |
| CAS | 1377049-84-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 91 mg/mL (103.1 mM) |
| References | 1. Kanda T. Hepatol Int. 2016 Jun 9. [Epub ahead of print] |