| Description | Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties. |
| molecular weight | N/A |
| Molecular formula | C13H16O3 |
| CAS | 80449-31-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 5.5 mg/ml, Sonication is recommended. |
| References | 1. Nakahama H , Kuribayashi K , Sugita M , et al. Cytoprotective effect of ulinastatin, a Kunitz-type protease inhibitor, on hypoxic injury in L2 cells treated with antimycin A via stabilization of lysosomal fragility.[J]. Pulmonary Pharmacology & Therapeutics, 1999, 12(1):1-6. 2. Li S T , Dai Q , Zhang S X , et al. Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cells by inhibiting the JNK/NF-κB signaling pathway and activating the PI3K/Akt/Nrf2 pathway[J]. Acta Pharmacologica Sinica, 2018. |
| Citations | 1. Bu C, Wang R, Wang Y, et al. Taraxasterol Inhibits Hyperactivation of Macrophages to Alleviate the Sepsis-induced Inflammatory Response of ARDS Rats. Cell Biochemistry and Biophysics. 2022: 1-8. |