| Description | Ulenistamab (PBP1510) is a first-in-class humanized IgG1 monoclonal antibody that targets the pancreatic adenocarcinoma upregulated factor (PAUF), and is utilized in pancreatic cancer (PC) research [1]. |
| In vitro | Ulenistamab (PBP1510) 对 PC 细胞系(CFPAC-1 和 BxPC-3)具有显著的抑制作用,有效阻止细胞的增殖,并明显降低了细胞迁移和侵袭的能力[1]。 |
| In vivo | 在6只猴子的单剂量研究中,评估了Ulenistamab (PBP1510)(最高20 mg/kg)的药代动力学(PK)特性和免疫原性。结果显示,在低剂量至高剂量范围内,猴子的全身暴露量与剂量成正比增加[1]。 |
| Synonyms | PBP1510 |
| molecular weight | N/A |
| CAS | 2415259-90-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 years | Shipping with blue ice. |