| Description | UK-59811 hydrochloride is a potent inhibitor of the Ca V Ab voltage-gated calcium channels in bacterial homotetrameric models. It is derived from Br-dihydropyridine, possessing significant inhibitory properties with an IC 50 of 194 nM. |
| Target activity | Cav Ab:194 nM (IC50) |
| molecular weight | 517.85 |
| Molecular formula | C22H30BrClN2O5 |
| CAS | 2250025-89-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lin Tang, et al. Structural basis for inhibition of a voltage-gated Ca 2+ channel by Ca 2+ antagonist drugs. Nature. 2016 Sep 1;537(7618):117-121. |