| Description | Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM). |
| In vitro | Ubiquitination-IN-1抑制A549细胞和HT1080细胞的活性，其半抑制浓度(IC50)分别为0.91 μM和0.4 μM。 |
| molecular weight | 429.42 |
| Molecular formula | C21H14F3N3O2S |
| CAS | 1819330-15-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/ml (139.72 mM), Sonication and heating to 60℃ are recommended. |
| References | 1. David Carroll, et al.Quinoline derivatives useful as ubiquitination inhibitors. WO2016025779A1. |