| Description | TYK2-IN-12 (compound 30) is a selective, orally active inhibitor of TYK2 (tyrosine kinase 2) (Ki: 0.51 nM). TYK2-IN-12 inhibits IL-12-induced IFNγ in human and mouse whole blood with IC50 values of 2.7 and 7.0 μM, respectively. 12 can be used to study psoriasis. |
| molecular weight | 434.44 |
| Molecular formula | C24H20F2N4O2 |
| CAS | 2244061-66-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |