| Description | TUN-92046 (Dimethyl 2-oxoglutarate) is a membrane-permeable alpha-ketoglutarate analogue that inhibits maladaptive autophagy in pressure overloading induced cardiomyopathy. |
| Synonyms | DM-α-KG, T71961, Dimethyl 2-ketoglutarate, Dimethyl 2-oxoglutarate |
| molecular weight | 174.15 |
| Molecular formula | C7H10O5 |
| CAS | 13192-04-6 |
| Storage | store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (287.11 mM) |
| References | 1. Faulkner A, et al. Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus. Diabetologia. 2020 Oct;63(10):2205-2217. |