| Description | Tulobuterol is mainly used for the prevention and treatment of bronchial asthma, asthmatic bronchitis and chronic bronchitis. Research shows that it could inhibit rhinovirus infection in primary cultures of human tracheal epithelial cells. |
| molecular weight | 227.73 |
| Molecular formula | C12H18ClNO |
| CAS | 41570-61-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Soluble |
| References | 1. Lin Q, Liu QH, Bao YX. [Efficacy and safety of tulobuterol patch versus oral salbutamol sulfate in children with mild or moderate acute attack of bronchial asthma: a comparative study]. Zhongguo Dang Dai Er Ke Za Zhi. 2013 Jun;15(6):462-5. Chinese. PubMed PMID: 23791063. 2. Yamaya M, Nishimura H, Nadine L, Kubo H, Ryoichi N. Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells. Physiol Rep. 2013 Aug;1(3):e00041. doi: 10.1002/phy2.41. Epub 2013 Aug 22. PubMed PMID: 24303127; PubMed Central PMCID: PMC3834998. 3. Ichikawa M, Kodama Y, Yoshimi K, Shiota S, Kotajima M, Nakajyo M, Seyama K, Fukuchi Y, Takahashi K. Effects of transdermal tulobuterol on dyspnea and respiratory function during exercise in patients with chronic obstructive pulmonary disease. J Thorac Dis. 2015 Apr;7(4):687-96. doi: 10.3978/j.issn.2072-1439.2015.04.22. PubMed PMID: 25973235; PubMed Central PMCID: PMC4419310. 4. Han X, Liu R, Ji L, Hui M, Li Q, Fang L, Bi K. Determination of tulobuterol in rat plasma using a liquid chromatography-tandem mass spectrometry method and its application to a pharmacokinetic study of tulobuterol patch. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jan 1;1008:108-114. doi: 10.1016/j.jchromb.2015.11.017. Epub 2015 Nov 28. PubMed PMID: 26638035. |