| Description | Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cell cycle arrest at the G2/M phase and triggering apoptosis. This compound exhibits anticancer activity by preventing tumor generation and inhibiting tumor proliferation and angiogenesis [1]. |
| molecular weight | 344.4 |
| Molecular formula | C20H24O5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |