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Tubulin polymerization-IN-22

CAS No.: 2493052-22-3

Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase as well as induces apoptosis. Tubulin polymerization-IN-22
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Description Tubulin polymerization-IN-22 arrests cell cycle at G2/M phase as well as induces apoptosis. Tubulin polymerization-IN-22 is an inhibitor of tubulin polymerization (IC 50 = 8.1 μM) [1].
In vitro Tubulin polymerization-IN-22 (Compound 4u) shows antiproliferative activity against human breast cancer cell line (MCF-7) with an IC50 of 1.47 μM [1]. Tubulin polymerization-IN-22 (Compound 4u) is a tubulin polymerization inhibitor by targeting the Colchicine binding site [1].
molecular weight 308.33
Molecular formula C19H16O4
CAS 2493052-22-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year