| Description | Tubulin inhibitor 12 (Hit 9) is a recently developed compound with potent inhibitory effects on tubulin (IC50 = 25.3 μM). This compound exhibits noteworthy anti-tumor and anti-proliferative activities, making it a promising candidate for the treatment of cancer [1]. |
| In vitro | Tubulin inhibitor 12 (0-100 μM; 72 h) shows moderate and broad-spectrum anti-proliferative activity [1]. Cell Proliferation Assay [1] Cell Line: HepG2, A549, and HCT116 cells Concentration: 0-100 μM Incubation Time: 72 hours Result: Showed IC 50 values of 49.13, 52.84, and 70.10 μM for HepG2, A549, and HCT116 cells, respectively. |
| molecular weight | 352.43 |
| Molecular formula | C24H20N2O |
| CAS | 92575-00-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |