| Description | Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum. |
| In vitro | Troxipide是一种新型抗溃疡化合物，对人类中性粒细胞迁移具有抑制作用，并对各种激动剂诱导的激活具有多重影响。它能抑制中性粒细胞介导的炎症和氧化应激，但不改善胃黏膜的组成和分泌。此外，它能增加前列腺素（一种细胞保护剂）的分泌。 |
| In vivo | Troxipide将增强胃粘膜的代谢和血液流动。 |
| Synonyms | 曲昔派特, 曲昔匹特, Aplace |
| molecular weight | 294.35 |
| Molecular formula | C15H22N2O4 |
| CAS | 30751-05-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 7.5 mg/mL (25.48 mM), Sonication is recommended. Ethanol: 3 mg/mL (10.19 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) |
| References | 1. Kusugami K, et al. Dig Liver Dis, 2000, 32(4), 305-311. 2. Dewan B, et al. Gastroenterol Res Pract, 2010; 2010: 758397. |