Description | Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml. |
In vitro | 化合物1的结构通过光谱学方法得以阐明,包括一系列二维核磁共振(2D nmr)技术的综合应用,涉及1H-1H COSY、异核检测的异核化学位移相关(HETCOR)变体、相敏感的NOESY以及长程HETCOR。 |
Target activity | HIV:3100 Nm(EC50) |
molecular weight | 318.45 |
Molecular formula | C20H30O3 |
CAS | 139122-81-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 3.18 mg/mL (10 mM), Sonication is recommended. |
References | 1. Anti-AIDS agents, 4. Tripterifordin, a novel anti-HIV principle from Tripterygium wilfordii: isolation and structural elucidation.J Nat Prod. 1992 Jan;55(1):88-92. |