Description | Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist that inhibits dihydrofolate reductase, which in turn blocks the synthesis of purine nucleotides and thymidylic acid, affecting DNA and RNA synthesis and exhibiting potential anti-tumour effects. |
molecular weight | 563.564 |
Molecular formula | C25H33N5O10 |
CAS | 82952-64-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |