| Description | Trimethoprim 3-oxide trimethoprim primary metabolite. |
| In vitro | In human liver microsomes (HLMs), Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates. The inhibitor of CYP1A α-Naphthoflavone inhibits Trimethoprim 3-oxide formation |
| Synonyms | Trimethoprim 3-N-oxide |
| molecular weight | 306.32 |
| Molecular formula | C14H18N4O4 |
| CAS | 27653-67-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Goldman JL, et al. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metab Dispos. 2015 Sep;43(9):1372-80. |