| Description | Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory response by suppressing the NF-κB signaling pathway.Trilobatin shows a strong inhibitory activity against α-glucosidase and a moderate inhibitory activity against α-amylase for management of postprandial hyperglycemia with less side effect. |
| Synonyms | 三叶苷, 三叶甙, P-Phlorizin |
| molecular weight | 436.41 |
| Molecular formula | C21H24O10 |
| CAS | 4192-90-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 79 mg/mL(181 mM) Ethanol: Soluble |
| References | 1. Fan X , Zhang Y , Dong H , et al. Trilobatin attenuates the LPS-mediated inflammatory response by suppressing the NF-κB signaling pathway[J]. Food Chemistry, 2015, 166:609-615. 2. Yang W M , Liu J K , Qin X D , et al. Antioxidant Activities of Three Dihydrochalcone Glucosides from Leaves of Lithocarpus pachyphyllus[J]. Zeitschrift für Naturforschung C, 2004, 59(7-8). |