| Description | Tribenoside (BG-356) is a vasoprotectant with mild anti-inflammatory, analgesic, and wound healing properties. |
| In vitro | 向HeLa细胞[2]施用1 nM-100 μM的Tribenoside表现出细胞毒性效应(EC50 = 13.74 μM)。 |
| In vivo | 通过口服方式每周给予500和1,200 mg/kg Tribenoside剂量显著减缓了雄性小鼠骨质疏松症的发展[3]。 |
| Target activity | Cytotoxic effect:13.74 µM (EC50, HeLa cells) |
| Synonyms | Glyvenol, Glyvenal, Ba 2140, BG-356, Glivenol, 三苄糖苷, TBGF |
| molecular weight | 478.58 |
| Molecular formula | C29H34O6 |
| CAS | 10310-32-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30 mg/mL (52.24 mM) Ethanol: 30 mg/mL (52.24 mM) DMF: 25 mg/mL (52.24 mM) |
| References | 1. Kikkawa Y, Takaki S, Matsuda Y, Okabe K, Taniguchi M, Oomachi K, Samejima T, Katagiri F, Hozumi K, Nomizu M. The influence of Tribenoside on expression and deposition of epidermal laminins in HaCaT cells. Biol Pharm Bull. 2010;33(2):307-10. 2. Yu-Chen Lo, et al. Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential. Sci Rep. 2017 Sep 12;7(1):11261. 3. G Wilhelmi, et al. Suitability of the C57 black mouse as an experimental animal for the study of skeletal changes due to ageing, with special reference to osteo-arthrosis and its response to tribenoside. Pharmacology. 1976;14(4):289-96. 4. Kalbhen DA, Scherbach E, Felten K. [Histology of the antiarthritic effect of tribenoside in experimental gonarthrosis]. Z Rheumatol. 1981 Mar-Apr;40(2):72-86. German. |